01Science and clinical evidence
Research, trials and relevant real-world findings test the rationale and expose unanswered questions.
Evidence and technology
Evidence, organised for better decisions.
Our assessment model brings scientific, clinical, regulatory, product, supply and market evidence into one structured review. Technology can help find patterns and gaps. People decide what matters.
01
Purpose
Better decisions, not more data.
Relevant evidence is scattered across sources and changes over time.
Evidence is organised around a defined development question. Computational tools can support search, classification and comparison, making relevant findings, contradictions and gaps easier to examine.
The objective is a documented basis for scientific, regulatory, product and commercial assessment, not an automated recommendation.
People remain accountable.
Relevant expertise is needed to assess limitations and uncertainty before any material development decision is made.
02
Evidence views
Four views build the picture.
01
02Regulation and development
Labels, regulatory records and programme history clarify precedent, requirements and earlier decisions.
03Product and supply
Formulation, manufacturing, availability and shortage information test whether a workable product route exists.
04Rights and market context
Rights, treatment practice, reimbursement and demand help establish whether the opportunity is viable in a specific territory.
03
Review model
A traceable route from question to decision.
- 01Define the question
- 02Collect relevant sources
- 03Compare the evidence
- 04Challenge with experts
- 05Decide the next step
The outcome may be to develop, gather more evidence, partner, monitor or stop. Recording why preserves the basis for later review.
04
Technology roles
Four useful roles for technology in review.
Organise
Classify sources by compound, disease, mechanism, evidence type and development question.
Connect
Map relationships between findings, outcomes, programme history and external conditions.
Compare
Review supportive, limiting and contradictory evidence against consistent criteria.
Prioritise
Make assumptions, gaps and trade-offs visible before an opportunity reaches expert review.
05
Responsible use
Keep the limits visible.
Keep conclusions traceable
Link material findings to their source, date and context.
Protect access
Apply appropriate controls to confidential, personal and licensed information.
Show uncertainty
Keep missing evidence, bias and method limitations visible to reviewers.
Record the decision
Document inputs, review steps and material judgements for later challenge.
Evidence to decision
Have a medicine opportunity that merits a closer look?