01Repurposing and new indications
Known compounds considered for another use when prior evidence supports a specific, testable question.
Therapeutic development
Developing new therapeutic options
We assess selected opportunities built on known science, improved products, in-licensed programmes or novel candidates where the evidence supports a credible next step.
01
Opportunities
Routes to a new medicine
The value lies in a defined clinical question and a feasible development route, not novelty alone.
01
02Reformulation and delivery
New formulations, routes or combinations designed to address a defined limitation in treatment.
03In-licensed programmes
Development assets that need additional evidence, a revised plan or new ownership to progress.
04Novel candidates
Selected new compounds where the need, science, rights and feasibility justify greater uncertainty.
02
Assessment
What makes a programme credible
A promising signal must hold up as a clinical, product and development proposition.
Clinical relevance
Is there a defined need, population and rationale for the proposed use?
Evidence and uncertainty
What do prior studies, safety information and contradictory findings support or leave unresolved?
Development path
Can the next study or regulatory step answer a meaningful question?
Product feasibility
Can the dose, formulation, analytical controls and manufacture support the proposed programme?
Rights and viability
Are the required rights, resources and route to appropriate patients available?
03
Next step
Set the next meaningful decision
- 01
Frame the question
Define the proposed use, population, product and decision required.
- 02
Address the critical gap
Choose the evidence, rights, regulatory or development work that can resolve it.
- 03
Plan execution
Assign responsibilities, quality controls, milestones and decision criteria.
- 04
Review the result
Progress, partner, monitor or stop according to the evidence and feasibility.
Assessment does not establish that an investigational medicine is safe, effective, approved or available.
Therapeutic opportunities
Have a repurposing candidate or development asset worth assessing?